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. 2019 May 7;19:425. doi: 10.1186/s12885-019-5614-4

Table 3.

Results of the EORTC QLQ-HN35 for head and neck cancer survivors. A comparison of the head and neck cancer patients with a report from the Swedish population [3]

Symptom scales/items Oral cancer
(n = 51)
Nasopharyngeal cancer
(n = 24)
Oropharyngeal cancer
(n = 15)
Hypopharyngeal cancer
(n = 10)
Laryngeal cancer
(n = 10)
Thyroid cancer
(n = 17)
Total
(n = 127)
Published Reference norm values
(n = 562)
p1 Published Head and neck cancer survivors
(n = 133)
p2
Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD)
Pain 10.13 (18.66) 6.60 (12.03) 11.67 (26.50) 4.17 (8.10) 7.5 (10.72) 3.92 (8.90) 8.14 (16.52) 3.0 (9.4) < 0.01 14.5 (19.8) < 0.01
Swallowing 9.80 (17.46) 9.72 (25.38) 18.33 (24.44) 8.33 (15.71) 14.17 (22.59) 6.37 (11.98) 10.56 (19.71) 2.0 (7.2) < 0.01 10.9 (19.6) 0.9
Sense problems 7.19 (18.33) 18.06 (25.97) 22.22 (24.13) 16.67 (19.25) 21.67 (32.44) 1.96 (5.54) 12.21 (21.87) 5.8 (16.1) < 0.01 20.5 (27.4) < 0.01
Speech problems 12.20 (19.41) 8.33 (15.46) 20 (25.27) 1.11 (19.91) 15.56 (28.30) 8.50 (8.36) 11.29 (19.50) 6.1 (13.2) < 0.01 12.1 (19.1) 0.73
Trouble with social eating 17.81 (27.64) 12.15 (21.14) 27.22 (30.78) 12.5 (20.88) 10.83 (26.07) 2.94 (10.18) 14.90 (25.04) 2.7 (10.0) < 0.01 11.7 (22.6) 0.28
Trouble with social contact 9.15 (18.81) 4.72 (11.37) 2.67 (6.07) 2.67 (4.66) 10.67 (24.78) 3.92 (5.80) 6.46 (15.05) 3.8 (10.6) 0.05 7.6 (14.7) 0.55
Less sexuality 12.75 (36.15) 11.11 (37.64) 31.11 (47.50) 6.67 (25.09) 10 (30.63) 10.78 (42.06) 13.65 (37.53) 26.1 (33.6) < 0.01 28.8 (36.3) < 0.01
Dental problems 32.68 (36.20) 27.78 (28.94) 20 (35.19) 43.33 (44.58) 23.33 (31.62) 13.73 (20.62) 27.82 (33.80) 10.1 (21.4) < 0.01 21.4 (32.3) 0.12
Mouth opening 32.68 (36.20) 27.78 (28.94) 20 (35.19) 43.33 (44.58) 23.33 (31.62) 13.73 (20.62) 27.82 (33.80) 1.8 (10.8) < 0.01 17.6 (29.3) < 0.01
Dry mouth 30.07 (39.58) 16.67 (26.01) 31.11 (36.66) 10 (22.50) 16.67 (32.39) 1.96 (8.09) 21.26 (33.51) 12.3 (22.3) < 0.01 47.3 (36.3) < 0.01
Sticky saliva 37.25 (38.09) 33.33 (31.08) 42.22 (36.66) 36.67 (39.91) 33.33 (31.43) 25.49 (27.71) 35.17 (34.71) 6.9 (17.5) < 0.01 18.6 (28.4) < 0.01
Coughing 20.92 (31.24) 31.94 (34.72) 53.33 (35.18) 23.33 (35.31) 20 (32.20) 13.73 (26.51) 25.98 (33.57) 16.8 (24.4) < 0.01 17.3 (24.6) 0.02
Malaise 17.65 (27.77) 18.06 (29.45) 24.44 (40.76) 20 (32.20) 16.67 (32.39) 17.65 (17.15) 18.64 (28.99) 11.3 (21.5) < 0.01 10.8 (20.0) 0.01

p1 P-value between the study population and the reference norm, p2 P-value between the study population and previously published head and neck cancer survivors