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Kaplan-Meier curves depicting the percentage of patients achieving DMARD-free sustained remission by treatment strategy. Kaplan-Meier curves depicting the achievement of DMARD-free sustained remission by treatment strategy in all included patients (a) and stratified by ACPA-status (b, c). DMARD, disease-modifying antirheumatic drug; HR, hazard ratio; ACPA, anticitrullinated protein antibodies; RF, rheumatoid factor; IT, intensive treatment; RC, routine care
