Table 4.
Correlation between Fecal Calprotectin and Reference Standard at Respective Locations
| Study | SB Crohn’s | LB Crohn’s | Reference standard/scoring system used | Key result | Comment |
|---|---|---|---|---|---|
| Jones [64] | 53 | 40 | SES-CD | Correlation in | Correlation noted only at LB location |
| SB: -0.01 (NS) | |||||
| LB: 0.8 (P<0.05) | |||||
| Lobatón [67] | 26 | 45 | CDEIS | Correlation in | - |
| SB: 0.437 (P=0.016) | |||||
| LB: 0.725 (P<0.01) | |||||
| Sipponen [71] | 16 | 17 | SES-CD | Correlation in | Correlation noted only at LB location |
| SB: 0.317 (NS) | |||||
| LB: 0.642 (P<0.01) | |||||
| Stawczyk-Eder [72] | 44 | 22 | SES-CD | Correlation with SES-CD in | - |
| SB: 0.78 (P<0.0001) | |||||
| LB: 0.78 (P<0.0002) | |||||
| Zittan [73] | 14 | 23 | SES-CD, MaRIA | Correlation in | Correlation noted only at LB location |
| SB: 0.4 (P=NS) | |||||
| LB: 0.61 (P<0.0001) |
SB, small bowel; LB, large bowel; SES-CD, Simple Endoscopic Score for Crohn’s Disease; CDEIS, Crohn’s Disease Endoscopic Index of Severity; MaRIA, magnetic resonance index of activity.