Table 3.

Predictors of Advanced Colorectal Neoplasm in the New Logistic Regression Model and the Associated Prediction Rule in the Derivation Cohort (n=41,702)

Variable	Coefficients	OR (95% CI)	P-value	Points assigned
Sex
Female		1 (Reference)		0
Male	0.1996	1.22 (0.95–1.56)	0.113	1
Age (yr)
<40		1 (Reference)		0
40–49	0.7142	2.04 (1.66–2.52)	<0.001	3
Alcohol
Never or non-heavy drinker		1 (Reference)		0
Heavy drinkera	0.3394	1.40 (1.13–1.74)	0.002	1
Smoking
Never or former smoker		1 (Reference)		0
Current smoker	0.3443	1.41 (1.14–1.75)	0.002	1
Obesity
No		1 (Reference)		0
Yesb	0.2543	1.29 (1.04–1.59)	0.018	1
HbA1c ≥6.5% or glucose ≥100 mg/dL
No		1 (Reference)		0
Yes	0.4377	1.55 (1.24–1.93)	<0.001	2
Family history of colorectal cancer
No		1 (Reference)		0
Yes	0.0843	1.09 (0.66–1.80)	0.743	1

^aMore than 4 times per week as heavy.

^bBMI ≥25 kg/m².

HbA1c, hemoglobin A1c.