Table 11.
Haplotypes | Controls | RVVI | p-value (controls vs RVVI)† | BV | p-value (controls vs BV)† | VVC | p-value (controls vs VVC)† | MI | p-value (controls vs MI)† | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n | Mean ± SD | n | Mean ± SD | n | Mean ± SD | n | Mean ± SD | n | Mean ± SD | |||||
5′H-10/3′H-2 | 24 | 836.70 ± 293.17 | 23 | 434.33 ± 190.36ab | 1.7 × 10−6*** | 9 | 466.93 ± 253.23 | 0.002** | 8 | 348.26 ± 113.77 | 1.9 × 10−7*** | 6 | 502.68 ± 148.28d | 0.001*** |
5′H-5/3′H-1 | 12 | 957.48 ± 453.28 | 16 | 857.95 ± 549.84a | 0.614 | 9 | 976.38 ± 598.13 | 0.935 | 3 | 296.06 ± 345.25 | 0.036* | 4 | 1042.5 ± 282.10d e | 0.733 |
5′H-3/3′H-3 | 15 | 1267.1 ± 418.30 | 10 | 714.96 ± 513.21 | 0.007** | 4 | 792.13 ± 657.76 | 0.090 | 3 | 541.73 ± 635.47 | 0.02* | 3 | 785.30 ± 260.96 | 0.076 |
5′H-1/3′H-1 | 14 | 1261.6 ± 612.37 | 10 | 795.10 ± 425.08 | 0.050* | 10 | 795.10 ± 425.08 | 0.050* | 0 | 0.00 ± 0.00 | NA | 0 | 0.00 ± 0.00 | NA |
5′H-9/3′H-1 | 15 | 1228.8 ± 545.30 | 8 | 729.92 ± 407.04 | 0.034* | 4 | 788.98 ± 463.87 | 0.160 | 2 | 796.85 ± 645.86 | NA | 2 | 544.88 ± 75.72 | NA |
5′H-1/3′H-2 | 9 | 999.78 ± 162.15 | 11 | 969.51 ± 530.29bc | 0.861 | 4 | 1113.4 ± 138.52 | 0.251 | 5 | 934.80 ± 788.63 | 0.864 | 2 | 768.50 ± 311.79 | NA |
5′H-35/3′H-3 | 4 | 1070.9 ± 362.48 | 11 | 389.29 ± 194.90c | 3.6 × 10−4*** | 5 | 363.78 ± 281.19 | 0.013* | 3 | 346.46 ± 51.56 | 0.026* | 3 | 466.14 ± 127.39e | 0.042* |
5′H-60/3′H-1 | 3 | 915.49 ± 320.84 | 11 | 735.61 ± 320.19 | 0.405 | 7 | 578.27 ± 174.35 | 0.057 | 3 | 576.38 ± 110.23 | 0.158 | 1 | 1159.05 ± 0.00 | NA |
p-value†† | 0.032* | 0.002** | 0.050* | 0.269 | 0.006** |
Haplotypes with n < 3 are not included in statistical analysis
* p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001
†Independent t-test between patients and controls as well as within groups
††One Way ANOVA with overall p-value followed by Post Hoc Tukey test that further indicates values with similar letter are significantly different
ap = 0.033, b p = 0.010, c p = 0.021, d p = 0.008, e p = 0.016