Table 3.
Parameter | Study inclusion (n = 12) | 6 months after study start (n = 10) | P-value* | 12 months after study start (n = 9) | P-value** |
---|---|---|---|---|---|
HR (bpm) | 93 ± 26 | 91 ± 18 | ns | 86 ± 19 | ns |
Systolic BP (mmHg) | 96 ± 18 | 104 ± 12 | ns | 97 ± 16 | ns |
Diastolic BP (mmHg) | 59 ± 12 | 60 ± 5 | ns | 57 ± 15 | ns |
LVESD (mm) | 20 ± 8 | 21 ± 7 | ns | 21 ± 8 | ns |
LVEDD (mm) | 31 ± 9 | 34 ± 8 | ns | 32 ± 9 | ns |
LVESV (ml) | 16 ± 14 | 18 ± 12 | ns | 19 ± 17 | ns |
LVEDV (ml) | 40 ± 28 | 53 ± 28 | 0.028 | 48 ± 33 | 0.011 |
SV (ml) | 25 ± 16 | 32 ± 17 | 0.022 | 30 ± 17 | 0.021 |
EF (%) | 68 ± 14 | 69 ± 14 | ns | 67 ± 10 | ns |
FS (%) | 38 ± 13 | 39 ± 11 | ns | 37 ± 7 | ns |
E/A | 1.3 ± 0.7 | 1.3 ± 0.7 | ns | 1.7 ± 0.6 | 0.018 |
IVRT (ms) | 115 ± 46 | 100 ± 42 | 0.047 | 94 ± 30 | 0.033 |
RVSP (mmHg) | 29 ± 8 | 30 ± 6 | ns | 30 ± 5 | ns |
Notes: A mitral Doppler A peak velocity, BP blood pressure, E mitral Doppler E peak velocity, EF ejection fraction, FS fractional shortening of LV, HR heart rate, IVRT isovolumetric relaxation time, LVEDD left ventricle end diastolic dimension, LVEDV left ventricle end diastolic volume, LVESD, left ventricle end systolic dimension, LVESV left ventricle end systolic volume, ns nonsignificance, RVSP right ventricle systolic pressure, SV stroke volume. Continuous data are expressed as mean ± SD. *6 months after study start vs study inclusion; **12 months after study start vs study inclusion