Table 5.
Population characteristics
| Author, year of publication | Patient’s characteristics | Teeth and defect characteristics at baseline | |||||
|---|---|---|---|---|---|---|---|
| Number of patients | Gender (m/f) | Mean age/ Range (years) | Type of periodontitis | Drop-out | Number/Type of tooth | Number/Type of defects | |
| A.Sculean et al. 1999a [56] | 16 | 10 m/6f | NA NA |
chronic periodontitisa | 0 | 32 NA |
32 2 to 3-wall intrabony defects |
| A.Sculean et al. 1999b [60] | 14 | NA | NA NA |
chronic periodontitis | 0 | 14 teeth scheduled for extraction |
14 advanced intrabony defects (teeth scheduled for extraction) |
| N. Donos et al. 2004 [62] | 9 | NA | NA 40–73 |
chronic periodontitis | 0 | 14 (EMD 4; GTR 3; EMD + GTR 7) mandibular molars |
14 degree III furcation-involved defects |
| P. Cortellini et al. 2005 [57] | 40 | 17 m/23f | 41.3 ± 10.7 NA |
chronic periodontitis | 0 | 40 (e-PTFE TrM 12; BM + BG 11; BM 7; EMD 10) NA |
40 intrabony defects 1-wall 1-wall 2 to 3-wall 3-wall |
| A. Crea et al. 2008 [61] | 40 | 19 m/21f | 45.8 35–66 |
chronic periodontitis | 1 | 40 (39 evaluable) anterior/posterior | 40 (39 evaluable) 3-wall intrabony defects |
| V. Iorio-Siciliano et al. 2011 [58] | 40 | 19 m/21f | NA 39–52 |
chronic periodontitis | 0 | 40 single-rooted teeth |
40 non- contained intrabony defects combination ≥80% 1-wall component (2 to 3-wall component in the most apical part) |
| V. Iorio-Siciliano et al. 2014 [59] | 40 | 18 m/22f | 44.4 33–57 |
chronic periodontitis | 0 | 40 single- and multi-rooted teeth |
40 non- contained intrabony defects combination ≥70% 1-wall component (2 to 3-wall component in the most apical part) |
BG bone graft, BM bioabsorbable membrane, EMD enamel matrix derivative, e-PTFE expanded polytetrafluoroethylene, f female, GTR guided tissue regeneration, m male, NA not available, PD probing depth, TrM titanium reinforced membrane
aconfirmed by the author (A.S)