Table 2.

Clinical, anthropometric and laboratory characteristics of studied groups

	Control group(mean ± SD) (n = 40)	Non-IR group (mean ± SD) (n = 25)	IR group (mean ± SD) (n = 35)	P 1	P2	P3
SBP (mm Hg)	125.4 ± 7.16	126.96 ± 8.33	133.2 ± 5.19	0.37	<0.001*	<0.001*
DBP (mm Hg)	85.6 ± 3.96	86.28 ± 4.39	88.37 ± 5.1	0.555	0.009	0.104
Hirsutism score	5.38 ± 0.594	7.34 ± 4.49	7.45 ± 1.2	<0.001*	<0.001*	0.893
Body mass index (kg/m2)	24.9 ± 2.48	29.1 ± 5.96	36.18 ± 3.2	<0.001*	<0.001*	<0.001*
Waist/hip ratio	0.98 ± 0.191	1.11 ± 0.28	1.36 ± 0.2	<0.05*	<0.001*	<0.001*
Ovarian volume	3.58 ± 0.612	7.2 ± 4.56	7.85 ± 1.437	<0.001*	<0.001*	0.467
AFC	2.58 ± 0.612	7.3 ± 4.02	7.37 ± 1.285	<0.001*	<0.001*	0.952
Total cholesterol (mg/dL)	167.5 ± 19.26	167.1 ± 25.15	197.8 ± 14.4	0.916	<0.001*	<0.001*
Triglycerides (mg/dL)	144.55 ± 20.4	193.2 ± 58.2	191.6 ± 25.9	<0.001*	<0.001*	0.883
LDL cholesterol (mg/dL)	106.24 ± 4.24	114.3 ± 17.4	134.06 ± 13.6	0.01	<0.001*	<0.001*
HDL cholesterol (mg/dL)	57.5 ± 7.33	45.8 ± 9.27	36.4 ± 7.48	<0.001*	<0.001*	<0.001*
Fasting plasma glucose (mg/dL)	83.9 ± 8.40	93.7 ± 16.19	96.4 ± 15.3	<0.001*	<0.001*	0.516
HbA1c (%)	5.5 ± 0.596	5.8 ± 0.171	6.18 ± 0.49	0.01	<0.001*	<0.001*
Fasting serum insulin (lU/mL)	6.8 ± 1.44	7.2 ± 1.29	24.97 ± 7.17	0.755	<0.001*	<0.001*
HOMA-IR	1.42 ± 0.322	1.65 ± 0.3	5.25 ± 1.92	0.448	<0.001*	<0.001*
HOMA-β	166.9 ± 76.9	149.3 ± 18.3	86.2 ± 22.5	0.384	<0.001*	<0.001*
FSH (mIU/mL)	4.8 ± 0.972	5.14 ± 1.27	5.85 ± 1.65	0.313	<0.001*	0.078
LH (mIU/mL)	5.52 ± 1.21	6.1 ± 1.2	7.59 ± 1.4	0.081	<0.001*	<0.001*
LH/FSH	1.2 ± 0.43	7.59 ± 1.4	1.3 ± 0.4	0.778	<0.001*	0.121
DHEA-S (mg/mL)	0.99 ± 0.31	0.99 ± 0.34	1.5 ± 0.91	0.967	<0.001*	<0.001*
Androstenedione (ng/mL)	1.17 ± 0.34	1.35 ± 0.48	2.07 ± 0.46	0.103	<0.001*	<0.001*
Total testosterone (ng/mL)	0.50 ± 0.145	0.62 ± 0.28	0.9 ± 0.3	0.062	<0.001*	<0.001*

IR; FSI fasting serum insulin, FPG fasting plasma glucose, AFC antral follicle cells, HOMA-IR homeostasis model assessments of insulin resistance, DHEA dehydroepiandrosterone

¹Significant P values (P < 0.05) when compared non-IR group with control group

²Significant P values (P < 0.05) when compared IR group with control group ³Significant P values (P < 0.05) when compared non-IR group with IR group