Table 2.
Univariate analysis of risk factors associated with postoperative AKI in patients with ADTIAD
| Variable | Statistics | OR (95%CI) | P-value |
|---|---|---|---|
| Age (year) | 47.8 ± 10.7 | 1.02 (0.98, 1.05) | 0.339 |
| Gender | |||
| male | 86 (74.78%) | 1.0 | |
| female | 29 (25.22%) | 1.35 (0.58, 3.17) | 0.487 |
| BMI (kg/m2) | 26.2 ± 3.9 | 1.18 (1.06, 1.33) | 0.003 |
| Diabetes mellitus | 7 (6.09%) | 5.78 (0.67, 49.62) | 0.110 |
| Hypertension | 92 (80.00%) | 1.30 (0.52, 3.24) | 0.576 |
| Previous cerebrovascular disease | 6 (5.22%) | 0.42 (0.07, 2.41) | 0.333 |
| Coronary artery disease | 6 (5.22%) | 0.88 (0.17, 4.55) | 0.878 |
| Smoking history | 56 (48.70%) | 1.83 (0.87, 3.85) | 0.110 |
| Drinking history | 23 (20.00%) | 0.96 (0.38, 2.39) | 0.926 |
| Hemopericardium | 19 (16.52%) | 0.98 (0.37, 2.63) | 0.969 |
| BUN (mmol/L) | 7.2 ± 2.5 | 1.03 (0.89, 1.19) | 0.722 |
| Preoperative sCr (umol/L) | 86.2 ± 29.07 | 1.01 (1.00, 1.02) | 0.147 |
| eGFR mL/(min·1.73m2) | 88.6 ± 22.6 | 0.98 (0.96, 1.00) | 0.013 |
| Hemoglobin (g/L) | 136.5 ± 17.3 | 1.00 (0.97, 1.02) | 0.686 |
| Hematocrit (%) | 39.4 ± 4.6 | 0.97 (0.89, 1.05) | 0.440 |
| LVEF (%) | 62.9 ± 6.1 | 1.03 (0.97, 1.10) | 0.354 |
| Renal artery dissection or occlusion | 17 (14.8%) | 0.57 (0.20, 1.62) | 0.292 |
| Penn class | |||
| Class Aa | 70 (60.9%) | 1.0 | |
| Non class Aa | 45 (39.1%) | 1.18 (0.56, 2.50) | 0.665 |
| Kidney malperfusion | 7 (6.1%) | 1.19 (0.25, 5.59) | 0.823 |
| AMI | 9 (7.8%) | 3.37 (0.67, 16.98) | 0.141 |
| Preoperative shock | 19 (16.5%) | 0.98 (0.37, 2.63) | 0.969 |
| CPB time | 211 ± 56 | 1.09 (1.01, 1.17) | 0.032 |
| Aortic cross clamp time (min) | 123.8 ± 42.6 | 1.00 (0.99, 1.01) | 0.401 |
| Bentall+TAR+FET | 47 (40.9%) | 1.01 (0.48,2.13) | 0.979 |
| Combined with CABG | 8 (7.0%) | 1.52 (0.35, 6.67) | 0.581 |
| Combined with aortic bypass surgery | 1 (0.9%) | a | 0.992 |
| Circulatory arrest time (min) | 27.4 ± 8.5 | 1.00 (0.96, 1.05) | 0.913 |
| Nasopharyngeal temperature (°C) at circulatory arrest | 22.9 ± 1.6 | 0.83 (0.65, 1.06) | 0.143 |
| Rectal temperature (°C) at circulatory arrest | 25.3 ± 2.1 | 0.92 (0.77, 1.10) | 0.356 |
| Intraoperative transfusion of PRBCs | 73 (63.5%) | 0.90 (0.42, 1.92) | 0.779 |
| Reoperation for bleeding | 9 (7.83%) | 8.00 (0.97, 66.21) | 0.054 |
Results are expressed as n (%) or mean ± SD or median [IQR]
AKI acute kidney injury, ADTIAD acute DeBakey Type I aortic dissection, AMI acute myocardial infarction, BMI body mass index, BUN blood urea nitrogen, CABG coronary artery bypass grafting, CPB cardiopulmonary bypass, eGFR estimated glomerular filtration rate, FET frozen elephant trunk, TAR total arch replacement, LVEF left ventricular ejection fraction, PRBCs packed red blood cells, sCr serum creatinine, SD standard deviation, IOR interquartile range
Bold value indicates significance at p < 0.05
aThe result failed because of the small sample size