Fig. 6. LGG treatment downregulates purine, nicotinate and nicotinamide metabolism pathways. A: Pathway analysis for downregulated metabolites in LGG treated day 8 pi in blood serum of neonates. B: Pathway analysis for downregulated metabolites in Salmonella challenged LGG treated day 8 pi in blood serum of neonates. Because of low volume, serum from 6 neonatal mice per treatment condition was pooled and the results presented are the average of 3 such pools (each of n = 6) per condition.