Table 1. Fold change values of significantly and differentially expressed genes as reported for treatment with LGG, challenge with ST and treatment with LGG following challenge with ST. Fold change values are computed with respect to time matched untreated (control) neonatal mice.
Fold change values (±SD) |
p-Values |
|||||
LGG | ST | LGGST | LGGST vs. ST | LGGST vs. LGG | ST-LGG | |
NOS2 | 4.7 ± 2.72 | 226.46 ± 70.7 | 13.5 ± 1.67 | 0.0004 | ns | 0.0003 |
IL1B | 18.24 ± 3.09 | 100.46 ± 8.06 | 3.72 ± 2.73 | <0.0001 | 0.0184 | <0.0001 |
T-bet | 0.74 ± 0.33 | 1.73 ± 0.37 | 0.79 ± 0.27 | 0.0144 | ns | 0.0102 |
TLR4 | 0.04 ± 0.01 | 16.48 ± 6.27 | 0.03 ± 0.03 | 0.0009 | ns | 0.0009 |
IL10 | 5.61 ± 0.16 | 3.55 ± 0.17 | 7.22 ± 0.64 | <0.0001 | 0.0019 | 0.0004 |
GATA3 | 1.71 ± 0.22 | 0.55 ± 0.06 | 1.04 ± 0.18 | 0.0159 | 0.0023 | <0.0001 |