Skip to main content
. 2013 Sep 3;3:2576. doi: 10.1038/srep02576

Table 1. Functional enrichment of DEGs based on gene ontology biological process terms.

Term Name Gene Num Benjamini p value Term Name Gene Num Benjamini p value
Function clusters of 429 DEGs
Cluster 1 (Enrichment Score: 7.30)          
Cell cycle 44 2.26E-08 Nuclear division 20 8.06E-06
Cell division 28 1.15E-07 M phase of mitotic cell cycle 20 1.01E-05
Cell cycle process 31 1.84E-06 Cell cycle phase 26 1.14E-05
M phase 25 4.33E-06 Organelle fission 20 1.08E-05
Mitosis 20 8.06E-06 Mitotic cell cycle 21 6.02E-05
Cluster 2 (Enrichment Score: 5.89)          
Nervous system development 47 5.25E-06 Developmental process 97 9.05E-05
Anatomical structure development 87 4.56E-06 Cellular developmental process 64 5.25E-04
System development 82 7.36E-06 Cell differentiation 62 5.40E-04
Multicellular organismal development 94 1.47E-05 Organ development 64 7.41E-04
Cluster 3 (Enrichment Score: 5.89)          
Nervous system development 47 5.25E-06 Neuron development 20 1.56E-03
Brain development 22 1.72E-04 Neuron differentiation 24 1.52E-03
Cell development 34 1.83E-04 Neuron projection development 17 1.50E-03
Generation of neurons 29 4.97E-04 Cell morphogenesis 19 8.65E-03
Cellular developmental process 64 5.25E-04 Cell morphogenesis involved in neuron differentiation 14 9.16E-03
Cell differentiation 62 5.40E-04 Cell morphogenesis involved in differentiation 15 1.13E-02
Central nervous system development 24 6.09E-04 Axonogenesis 13 1.12E-02
Neurogenesis 30 6.26E-04 Neuron projection morphogenesis 13 2.01E-02
Function clusters of 341 DEMGs&DEGs
Cluster 1 (Enrichment Score: 4.05)          
Nervous system development 35 8.34E-03 Developmental process 75 7.25E-03
Multicellular organismal development 73 5.37E-03 Cell development 26 1.16E-02
Anatomical structure development 65 3.82E-03 Cell differentiation 47 3.47E-02
System development 61 4.08E-03 Cellular developmental process 47 4.72E-02
Cluster 2 (Enrichment Score: 2.91)          
Nervous system development 35 8.34E-03 Generation of neurons 21 4.56E-02
Cell development 26 1.16E-02 Brain development 15 4.77E-02
Neuron differentiation 19 3.13E-02 Neuron development 15 4.65E-02
Cell differentiation 47 3.47E-02 Cellular developmental process 47 4.72E-02
Neuron projection development 13 4.82E-02 Forebrain development 11 4.55E-02
Function clusters of 88 other DEGs
Cluster 1 (Enrichment Score: 8.90)          
Cell cycle 21 1.03E-09 Mitotic cell cycle 13 1.36E-07
Cell cycle process 17 5.69E-09 M phase of mitotic cell cycle 12 1.38E-07
Cell division 14 8.64E-08 Organelle fission 12 1.40E-07
Nuclear division 12 1.66E-07 Cell cycle phase 14 2.15E-07
Mitosis 12 1.66E-07 M phase 13 4.06E-07
Cluster 2 (Enrichment Score: 3.47)          
Chromosome segregation 8 1.24E-06 Sister chromatid segregation 4 5.21E-03
Mitotic sister chromatid segregation 4 4.74E-03 Mitotic metaphase plate congression 3 7.22E-03