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Genetic studies in male infertility between 1958 and 2018. (A) Graphical overview of genetic studies in male infertility. (B) Graphical representation of type of genetic research in male infertility. (C) The use of Sanger sequencing and next-generation sequencing for the discovery of genes in male infertility. (D) Increase of genes linked to human male infertility. AZF, azoospermia factor; CNV, copy number variants.
