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A schematic diagram Endoplasmic reticulum stress and insulin signaling pathway in insulin resistance.
Abbreviations: Akt, protein kinase B; ATF-6, activating transcription factor 6; ATF-4, activating transcription factor 4; GSK-3β, glycogen synthase kinase 3 beta; PERK, protein kinase-like endoplasmic reticulum kinase; TRIB3, tribbles homolog 3.
