Table 1.

Effect of stretch on glutathione and enzymes involved in glutathione redox cycle in the 158N cell line after tensile strain of 20% and 30%

	Ctrl	Stretch	p value
20% strain model
GSH (AU)	403.7 ± 9.02	363.3 ± 4.41*	0.0159
GPx (U/mg)	0.392 ± 0.039	0.216 ± 0.024**	0.0020
GR (U/mg)	0.018 ± 0.005	0.050 ± 0.020	0.1408
30% strain model
GSH (AU)	421.2 ± 10.13	370.8 ± 7.51**	0.0026
GPx (U/mg)	0.327 ± 0.014	0.272 ± 0.015*	0.0247
GR (U/mg)	0.013 ± 0.003	0.030 ± 0.006	0.0668

Reduced (GSH) and oxidized (GSSG) glutathione, glutathione peroxidase (GPx), and glutathione reductase (GR) were measured in control (Ctrl) and stretched (Stretch) cells following strain of 20% and 30%. GSSG was not detectable in our system. Results represent the mean ± SEM (n = 9 for 20% and n = 6 for 30%)

*p < 0.05; **p < 0.01