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. 2019 May 1;30(5):420–435. doi: 10.5152/tjg.2019.18693

Table 7.

ITT eradication rate for the 7-day treatment

I2 Effectiveness 0, 95% LCL 0, 95% UCL p
Average risk ratio (LAC) 2.11 1.47 3.05
Event rate (LAC) (fixed-effects model) 0.00 (p=0.671) 0.68 0.50 0.78 0.002
Average risk ratio (OAC) 1.21 0.19 7.79
Event rate (OAC) (random-effects model) 86.94 (p=0.006) 0.55 0.15 0.90 0.837
Average risk ratio (PAC) 1.19 0.77 1.86
Event rate (PAC) (fixed-effects model) 48.05 (p=0.146) 0.50 0.48 0.64 0.123

Table 7 shows that studies carried out using the ITT analysis were divided into subgroups according to PPIs with a treatment duration of 7 days. According to this, although the effect magnitudes of studies using the PAC and OAC combinations were found to be insignificant, the effect for the LAC combination was significant.