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. 2013 Oct 17;3:2972. doi: 10.1038/srep02972

Figure 2. Non-parametric correlations and functional connectivity analysis.

Figure 2

(2a) When the ranked number of times NFL alumni had been sent off the field due to head injury (Ranked Times Off - RTO) was used to predict activation during the SP task in a non-parametric permutation analysis, extensive clusters of activation were evident in the right DLPFC extending into the FPC. A more focal cluster was also evident within the PC (image rendered at p < 0·01 uncorrected with FWE cluster correction within a mask that includes all regions that are active during task relative to rest – see table 1c). (2b) When beta weights for the physiological predictor function were contrasted across groups, NFL alumni showed generally lowered functional connectivity between the right DLPFC seed region and the left DLPFC, the right FPC and the PC bilaterally. Yellow regions show the t-test of beta weights for the physiological predictor collapsed across participants with FWE voxel-wise correction of p < 0·05 for the whole brain mass t and p values report cross-group analyses for the indicated connections.