Figure 3A:

Distribution of proteins encoded by these identified genes and 34% of proteins are located in the membrane, 15% at the cytoplasm, 12% at the nucleus, 7% at an extracellular region, 5% at the collagen, 3% at the cytoskeleton, 2% at the microtubule, and 22% at other areas. The results suggest that potential causative factors of AD pathology may be associated with the proteins located at the membranes of neurons, cytoplasms, and nuclei and extracellular regions (particularly at the membrane and cytoplasm).