Table 2. Distribution of non-polio EV types and species among healthy children and acute flaccid paralysis patients in the Kasai Oriental and Maniema provinces of the Democratic Republic of Congo.
Virus isolates | |||||||
---|---|---|---|---|---|---|---|
Healthy children (N = 78 isolates) | AFP patients (N = 150 isolates) |
Total (N = 228 isolates) |
|||||
types/species | n* | % | n | % | n | % | |
HEV-A | |||||||
EV-A76 | 1 | 0.7 | 1 | 0.5 | |||
All EV-A isolates | 1 | 0.7 | 1 | 0.5 | |||
EV-B | |||||||
CV-B1 | 2 | 1.4 | 2 | 1.0 | |||
CV-B2 | 1 | 1.4 | 3 | 2.1 | 4 | 1.9 | |
CV-B3* | 16 | 23.2 | 3 | 2.1 | 19 | 9.1 | |
CV-B4* | 12 | 17.4 | 3 | 2.1 | 15 | 7.2 | |
CV-B5 | 1 | 1.4 | 6 | 4.3 | 7 | 3.3 | |
CV-B6 | 2 | 2.9 | 4 | 2.9 | 6 | 2.9 | |
E-1 | 2 | 2.9 | 6 | 4.3 | 8 | 3.8 | |
E-2 | 2 | 1.4 | 2 | 1.0 | |||
E-3 | 3 | 4.3 | 7 | 5.0 | 10 | 4.8 | |
E-4 | 1 | 0.7 | 1 | 0.5 | |||
E-6 | 1 | 1.4 | 15 | 10.7 | 16 | 7.7 | |
E-7 | 6 | 4.3 | 6 | 2.9 | |||
E-11* | 2 | 2.9 | 24 | 17.1 | 26 | 12.4 | |
E-12 | 9 | 6.4 | 9 | 4.3 | |||
E-13 | 1 | 1.4 | 6 | 4.3 | 7 | 3.3 | |
E-14 | 7 | 5.0 | 7 | 3.3 | |||
E-19 | 1 | 0.7 | 1 | 0.5 | |||
E-20 | 4 | 2.9 | 4 | 1.9 | |||
E-21 | 1 | 0.7 | 1 | 0.5 | |||
E-24 | 4 | 5.8 | 5 | 3.6 | 9 | 4.3 | |
E-25 | 2 | 2.9 | 2 | 1.0 | |||
E-29 | 4 | 2.9 | 4 | 1.9 | |||
E-31 | 2 | 1.4 | 2 | 1.0 | |||
E-33 | 4 | 2.9 | 4 | 1.9 | |||
EV-B69 | 2 | 2.9 | 1 | 0.7 | 3 | 1.4 | |
EV-B74 | 1 | 0.7 | 1 | 0.5 | |||
EV-B75 | 1 | 1.4 | 7 | 5.0 | 8 | 3.8 | |
EV-B93 | 2 | 1.4 | 2 | 1.0 | |||
EV-B97 | 1 | 0.7 | 1 | 0.5 | |||
All EV-B isolates | 50 | 72.5 | 137 | 97.9 | 187 | 89.5 | |
EV-C | |||||||
CV-A13 | 13 | 18.8 | 13 | 6.2 | |||
CV-A17 | 1 | 1.4 | 1 | 0.5 | |||
CV-A20 | 5 | 7.2 | 5 | 2.4 | |||
EV-C99 | 1 | 0.7 | 1 | 0.5 | |||
All EV-C isolates | 19 | 27.5 | 1 | 0.7 | 20 | 9.6 | |
EV-D | |||||||
EV-D111 | 1 | 0.7 | 1 | 0.5 | |||
All EV-D isolates | 0.0 | 1 | 0.7 | 1 | 0.5 | ||
All isolates typed | 69 | 100.0 | 140 | 100.0 | 209 | 100.0 | |
Mixing strains | 3 | 3.8 | 10 | 6.7 | 13 | 5.7 | |
Same isolate on RD and HEP-2c | 6 | 7.7 | na | na | na | na | |
All isolates | 78 | 100.0 | 150 | 100.0 | 228 | 100.0 |
N, total number of isolates; n, number of isolates in each type; %, percentage among all typed isolates
*, Among the 19 healthy children from whom 19 RD and 19 HEp-2c derived isolates were obtained, thirteen showed heterotypic isolates while the remaining six contained the same virus type from RD and HEp-2c cell lines. The number of EV types specified by a star includes only one of the homotypic isolates recovered from the same child using RD and HEp-2c cell lines, respectively.
na, not applicable