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. 2019 Apr 19;13(4):e0007335. doi: 10.1371/journal.pntd.0007335

Table 2. Distribution of non-polio EV types and species among healthy children and acute flaccid paralysis patients in the Kasai Oriental and Maniema provinces of the Democratic Republic of Congo.

  Virus isolates
Healthy children (N = 78 isolates) AFP patients
(N = 150 isolates)
Total
(N = 228 isolates)
types/species n* % n % n %
HEV-A
EV-A76     1 0.7 1 0.5
All EV-A isolates 1 0.7 1 0.5
EV-B
CV-B1     2 1.4   2 1.0
CV-B2 1 1.4 3 2.1 4 1.9
CV-B3* 16 23.2 3 2.1 19 9.1
CV-B4* 12 17.4 3 2.1 15 7.2
CV-B5 1 1.4 6 4.3 7 3.3
CV-B6 2 2.9 4 2.9 6 2.9
E-1 2 2.9 6 4.3 8 3.8
E-2 2 1.4 2 1.0
E-3 3 4.3 7 5.0 10 4.8
E-4 1 0.7 1 0.5
E-6 1 1.4 15 10.7 16 7.7
E-7 6 4.3 6 2.9
E-11* 2 2.9 24 17.1 26 12.4
E-12 9 6.4 9 4.3
E-13 1 1.4 6 4.3 7 3.3
E-14 7 5.0 7 3.3
E-19   1 0.7 1 0.5
E-20 4 2.9 4 1.9
E-21     1 0.7 1 0.5
E-24 4 5.8 5 3.6 9 4.3
E-25 2 2.9   2 1.0
E-29 4 2.9 4 1.9
E-31     2 1.4 2 1.0
E-33 4 2.9 4 1.9
EV-B69 2 2.9 1 0.7 3 1.4
EV-B74 1 0.7 1 0.5
EV-B75 1 1.4 7 5.0 8 3.8
EV-B93 2 1.4 2 1.0
EV-B97 1 0.7 1 0.5
All EV-B isolates 50 72.5 137 97.9 187 89.5
EV-C
CV-A13 13 18.8   13 6.2
CV-A17 1 1.4 1 0.5
CV-A20 5 7.2   5 2.4
EV-C99 1 0.7 1 0.5
All EV-C isolates 19 27.5 1 0.7 20 9.6
EV-D
EV-D111   1 0.7 1 0.5
All EV-D isolates   0.0 1 0.7 1 0.5
All isolates typed 69 100.0 140 100.0 209 100.0
Mixing strains 3 3.8 10 6.7 13 5.7
Same isolate on RD and HEP-2c 6 7.7 na na na na
All isolates 78 100.0 150 100.0 228 100.0

N, total number of isolates; n, number of isolates in each type; %, percentage among all typed isolates

*, Among the 19 healthy children from whom 19 RD and 19 HEp-2c derived isolates were obtained, thirteen showed heterotypic isolates while the remaining six contained the same virus type from RD and HEp-2c cell lines. The number of EV types specified by a star includes only one of the homotypic isolates recovered from the same child using RD and HEp-2c cell lines, respectively.

na, not applicable