Fig 4. In vivo voxel based morphometry identified a significant interaction between time and training.

Trained animals showed significant enlargement prominently in the contralateral (but also ipsilateral) cingulate cortex (A24, and 29), M1, S1, and the visual cortex (V1). The contralateral hippocampus, and corpus callosum, under the M1 were also enlarged. Results are presented as tmaps, FDR cluster-corrected for multiple comparisons using an initial cluster forming threshold of 0.05 significance, and the whole brain as a mask (green color). Uncorrected statistical maps (yellow) suggested involvement of the ipsilateral hemisphere.