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. 2019 May 8;14(5):e0216569. doi: 10.1371/journal.pone.0216569

Fig 4. Ureaplasma-driven mRNA expression of pro-inflammatory cytokines in A549 cells and HPMEC.

Fig 4

In A549 cells, mRNA levels of TNF-α (a), IL-1β (b), IL-6 (c), and IL-8 (d) were assessed via qRT-PCR after 4 and 30 h stimulation. Similarly, mRNA expression in HPMEC was determined for TNF-α (e), IL-1β (f), IL-6 (g), and IL-8 (h). Data are presented as means ± SD from n ≥ 3 independent experiments. LPS stimulated cells were compared vs. control, cells exposed to Ureaplasma isolates vs. control and vs. broth. * p < 0.05, ** p < 0.01, and *** p < 0.001 compared to untreated controls; ††† p < 0.001 compared to cells treated with broth. SV8: Ureaplasma urealyticum serovar 8, SV3: Ureaplasma parvum serovar 3.