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. Author manuscript; available in PMC: 2020 Apr 23.
Published in final edited form as: ACS Nano. 2019 Apr 12;13(4):4778–4794. doi: 10.1021/acsnano.9b01444

Table 1.

Comparison of different NP formulations for hydrodynamic size, zeta potential, OVA content, ligand content and molar ratios.

Nanoparticle Hydrodynamic size (nm) Polydispersity index (PDI) Zeta potential (mV) OVA content (μg/mg NPs) Ligand content (μg/mg NPs) mol% of PLGA
NP only 231.2 ± 2.17 0.096 −42.55 ± 2.99 NA NA NA
NPOVA 246.5 ± 3.01 0.105 −44.37 ± 2.81 51.61 ± 2.32 NA NA
NPOVA/mannc 279.5 ± 2.74 0.121 −51.63 ± 4.05 50.31 ± 3.52 139 ± 21 NA
NPOVA/manc 297.2 ± 2.98 0.113 −54.82 ± 5.18 50.98 ± 3.88 346 ± 52 NA
NPOVA/ApoBPlo 268.8 ± 4.96 0.109 −8.63 ± 1.38 50.77 ± 3.08 6.86 ± 0.89 2.8
NPOVA/ApoBPhi 270.8 ± 4.96 0.113 −4.56 ± 2.25 50.12 ± 2.18 12.96 ± 0.77 5.3