Skip to main content
. Author manuscript; available in PMC: 2020 Apr 17.
Published in final edited form as: Vaccine. 2019 Mar 27;37(17):2322–2330. doi: 10.1016/j.vaccine.2019.03.044

Figure 2. IL-33 impacts the quality of the Env-specific antibody response.

Figure 2.

A. CN54 gp120-specific plasma IgG1 and IgG2b was determined by ELISA. Symbols represent individual mice. Lines indicate significant difference (p<0.05) between groups. B. Avidity index of CN54 gp120-specific plasma IgG determine by ELISA in the absence or presence of 8M urea treatment. Symbols represent individual mice. * indicates significant difference (p<0.05) between groups as determined by two-tailed Mann-Whitney test. C. Plasma (wk 12) was evaluated for IgM and IgG binding to indicated Env by ELISA. Symbols represent group mean ± SD fold increase in titer compared to the non-immunized group (X/NI). NI: n=16, Alum only: n=16, MPLA: n=11, IL-33: n=5. Data are representative of three independent experiments.