Figure 2. Effects of fucoxanthin on body weight and number of colorectal polyps in AOM/DSS mice. (A) Experimental protocol with fucoxanthin (Fx) in AOM/DSS mice. Fx oil (fucoxanthin-5™) was administrated at 30 or 6 mg Fx/kg every 2-3 days for 8 weeks (black arrows). The control groups with or without AOM/DSS treatment was given the equivalent volume (μL) of control oil (without Fx). (B) Body weight changes from the day after DSS intake to the day of final Fx administration. (C) Polyps numbers. Means±SE (n=8-10). (*) p<0.05 by one-way ANOVA with post-hoc Tukey-Kramer test.