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. Author manuscript; available in PMC: 2020 May 7.
Published in final edited form as: Anal Chem. 2019 Apr 12;91(9):6233–6241. doi: 10.1021/acs.analchem.9b00938

Figure 3.

Figure 3.

Down-regulation of SAR1B in CRC confers worse patient prognosis and associates with higher disease stages. Comparison of SAR1B expression levels in paired CRC tissues (CRC) with adjacent nontumor tissues (normal) in (A) TCGA-COAD (n = 50) and (B) GSE21510 (n = 44) cohorts. The p values were calculated by using a paired two-tailed Student’s t test (****, p < 0.0001). Kaplan–Meier survival analysis of CRC patients stratified by the median SAR1B mRNA expression in (C) GSE17536 (n = 232) and (D) GSE39582 (n = 585) cohorts. The log-rank (Mantel–Cox) test was used to calculate the p values. (E) Correlation of SAR1B mRNA expression with different CRC stages in the GSE39582 (n = 585) cohort. The p values were calculated by using an unpaired two-tailed Student’s t test (*, 0.01 ≤ p < 0.05).