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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Histopathology. 2019 Apr 25;74(7):1088–1097. doi: 10.1111/his.13840

Table 4.

Multivariable Cox proportional hazards model for the independent association of bronchiolocentric fibrosis with overall survival in the total cohort and the cohort diagnosed with idiopathic pulmonary fibrosis.

Total cohort (n=252) Hazard ratio 95%CI P value
Bronchiolocentric fibrosis 0.68 ( 0.41, 1.13 ) 0.13
Age 1.03 ( 1.00, 1.06 ) 0.06
Male 0.92 ( 0.55, 1.55 ) 0.75
Ever-smoking 1.40 ( 0.87, 2.25 ) 0.17
IPF 1.40 ( 0.72, 2.74 ) 0.32
GERD 0.59 ( 0.36, 0.95 ) 0.03
%FVC 0.98 ( 0.96, 0.99 ) 0.004
%DLCO 0.99 ( 0.98, 1.01 ) 0.22

IPF cohort (n=215)

Bronchiolocentric fibrosis 0.82 ( 0.48, 1.40 ) 0.47
Age 1.03 ( 1.00, 1.06 ) 0.08
Male 1.01 ( 0.56, 1.81 ) 0.97
Ever-smoking 1.12 ( 0.68, 1.86 ) 0.65
GERD 0.60 ( 0.36, 1.01 ) 0.06
%FVC 0.98 ( 0.96, 0.99 ) 0.01
%DLCO 0.98 ( 0.97, 1.00 ) 0.11