Figure 6.

Immune capture with biotinylated anti-CSPG4 Abs of melanoma-derived exosomes (MTEX) on avidin-labeled beads from plasma of patients with melanoma. Non-captured exosomes were re-captured with anti-CD63 Abs for detection by on-bead flow cytometry. Two different anti-CSPG4 Abs (mAb 763.74 and mAb 225.28) specific for distinct epitopes of CSPG4 were used for capture and detection, respectively). Reproduced from Sharma P. et al., ref. 39 under the terms of Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0/.