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Marburg VP40 undergoing substantial conformational rearrangements upon binding to the membrane. (A-C) Snapshots of the VP40 dimer association with the plasma membrane at different time points. (D) Various lipid types interacting with the basic loop 1 and basic loop 2 residues at 300 ns. The lipids are colored as: POPS-cyan, POPI-green, POPC-gray, POPE-purple. Adapted with permission from ref 675. Copyright 2017 The Royal Society of Chemistry.
