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. Author manuscript; available in PMC: 2020 May 8.
Published in final edited form as: Chem Rev. 2019 Apr 12;119(9):6086–6161. doi: 10.1021/acs.chemrev.8b00608

Figure 38.

Figure 38

Snapshots from a 4 μs CG simulation of the assembly of an HDL particle with lipids initially randomly scattered. At the end of 4 μs, the simulation captured a discoidal particle with beltlike arrangement of the scaffold proteins. The two scaffold proteins (backbone only), are shown in blue and red, and the DPPC lipids are shown in dark and light tan. Reprinted with permission from ref 688. Copyright 2007 Elsevier.