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. Author manuscript; available in PMC: 2020 May 7.
Published in final edited form as: Cell Metab. 2019 Mar 21;29(5):1192–1205.e8. doi: 10.1016/j.cmet.2019.02.013

Figure 6. Effects of mTORC1 and tissue-specific DAF-16 on food consumption.

Figure 6.

(A) Effects of mTOR signaling on bacterial food intake. Inhibition of mTORC1-specific genes did not affect feeding, and the small increase seen with let-363 RNAi might reflect inhibition of the related but distinct complex mTORC2 (Saxton and Sabatini, 2017), as suggested by the effect of rict-1 (Rictor) RNAi.

(B) Tissue-specific activities of DAF-16 in the regulation of food intake. DAF-16 is expressed from transgenes in the intestine (ges-1) or neurons (unc-119), or from its own promoter (Pdaf-16) (Libina et al., 2003).

Mean ± SEM, two-tailed t-test. * P < 0.05, ** P < 0.01, *** P < 0.0001.