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. Author manuscript; available in PMC: 2020 May 8.
Published before final editing as: JACC Cardiovasc Imaging. 2018 Nov 8:S1936-878X(18)30920-3. doi: 10.1016/j.jcmg.2018.08.038

Figure 3. Mediation analysis - amygdalar, bone marrow, and vascular disease in psoriasis (N=164).

Figure 3

A) Mediation analyses showing the indirect effect of bone marrow activity on the relationship between resting amygdalar and aortic vascular inflammatory activity.

B) Mediation analyses showing the added effect of bone marrow activity on the relationship between resting amygdalar activity and non-calcified coronary plaque burden.

*TBR: Target-to-background ratio; SUV: Standardized uptake value. Blue arrow: Total effect, Yellow arrow: Direct effect, Green arrow: Indirect effect

**Likelihood ratio test: A) χ2=18.33, p<0.001, B) χ2=87.50, p<0.001

***Model adjusted for Framingham risk score, waist-to-hip ratio, lipid treatment and C-reactive protein.