FIG 4.

Kaplan-Meier plots of the effect of tumor mutational burden (TMB) status on overall survival. Log-rank P values are reported from an unadjusted analysis. The results refer to all patients for whom mutational analysis was available, which includes pre-KRAS amendment and post-KRAS amendment patients. In TMB-high tumors, the proportions of right and transverse and left tumors were 45.1% and 54.9%, respectively. In TMB-low tumors, the proportions of right and transverse and left tumors were 40.3% and 59.7%, respectively.