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Independent validation of high cyclin E1 (CCNE1) mRNA as a marker of palbociclib resistance in the Modulation of Rb Phosphorylation and Antiproliferative Response to Palbociclib: The Preoperative-Palbociclib (POP) Randomized Clinical Trial. (A) Antiproliferative response by CCNE1 expression tertile. (B) Geometric mean change in protein encoded by the MKI67 gene (Ki-67) expression with palbociclib treatment by CCNE1 expression tertile.
