Table 1.
Creatine kinase and calcium plasma levels and renal function parameters of control and experimental groups, 4 days after saline or glycerol injections.
| Control | Control + Calcitriol | Glycerol | Glycerol + Calcitriol | |
|---|---|---|---|---|
| CK | 26.79 ± 1.59 | 24.57 ± 4.89 | 44.23 ± 7.51*,+ | 45.42±3.13*,+ |
| Ca2+ | 10.04 ± 0.50 | 9.507 ± 0.41 | 8.144 ± 0.50 | 8.373 ± 0.19 |
| Cr | 0.610 ± 0.03 | 0.620 ± 0.05 | 2.73 ± 0.39*,+ | 2.07±0.43*,+ |
| GFR | 0.421 ± 0.06 | 0.490 ± 0.03 | 0.113 ± 0.02*,+ | 0.240 ± 0.04*,+,# |
| FENa+ (%) | 0.290 ± 0.06 | 0.317 ± 0.05 | 3.713±0.51*,+ | 1.96±0.64+,# |
| Uosm | 2080±241.6 | 1809±117.9 | 541.5±25.49*,+ | 696.0±33.45*,+ |
| V | 0.004 (0.002;0.01) | 0.005 (0.003;0.01) | 0.020 (0.01;0.02)*,+ | 0.013 (0.007;0.01)*,+,# |
CK, plasma creatine kinase (U/L); Ca2+, plasma calcium (mg/dL); Cr, plasma creatinine (mg%); GFR, glomerular filtration rate (ml min−1100 g−1); FENa+, fractional sodium excretion (%); Uosm, urinary osmolality (mOsm kg H2O−1); V, urinary flow (mL/min). The data are expressed as the mean ± SEM (GFR, FENa+ and Uosm) or median and interquartile range (25–75%). n = 7–12 per group. *P < 0.05 compared to Control; +P < 0.05 compared to Control +Calcitriol; #P < 0.05 compared to Glycerol.