Table 4.

Adjusted odds ratios from logistic regression model of FAMCAT with continuous values for all lipid measurements and age with inclusion of personal history of premature myocardial infarction

	Men (n=362 769)	Women (n=384 231)
Highest cholesterol recorded, mmol/L
If LDL cholesterol measured	2·57 (2·43–2·73)	3·29 (3·13–3·47)
If total cholesterol measured	1·70 (1·61–1·80)	1·95 (1·83–2·07)
Age during cholesterol measurements, years	0·97 (0·96–0·98)	0·99 (0·98–1·00)
Log triglycerides during cholesterol measurement, mmol/L	0·16 (0·13–0·19)	0·08 (0·06–0·09)
Lipid-lowering drugs prescribed during cholesterol measurement*
Prescribed fibrate, bile acid sequestrant, or nicotinic acid	7·03 (2·42–20·36)	3·98 (1·20–13·28)
Prescribed low-potency statin†	1·03 (0·25–4·18)	3·54 (1·72–7·30)
Prescribed medium-potency statin‡	1·64 (1·29–2·41)	1·72 (1·03–2·87)
Prescribed high-potency statin§	1·75 (0·79–3·91)	2·55 (1·32–4·91)
Previously history of premature myocardial infarction*‖	2·30 (1·49–3·53)	1·54 (0·79–3·00)
Family history of familial hypercholesterolaemia*	6·74 (3·98–11·39)	2·49 (1·46–2·25)
Family history of myocardial infarction*	3·53 (2·24–5·57)	4·37 (3·17–6·04)
Family history of raised cholesterol*	2·80 (1·69–4·64)	2·12 (1·40–3·22)
Diabetes diagnosis*	0·25 (0·13–0·46)	0·46 (0·29–0·74)
Chronic kidney disease diagnosis*	0·77 (0·46–1·32)	0·17 (0·10–0·30)

Data are adjusted odds ratios (95% CI). Full regression coefficients are presented in the appendix p 3. FAMCAT=familial hypercholesterolaemia case ascertainment tool.

^*Compared with reference group (odds ratio 1).

^†Fluvastatin or pravastatin 40 mg per day, or simvastatin 10 mg per day.

^‡Fluvastatin or pravastatin 80 mg per day, simvastatin 20–40 mg per day, atorvastatin 10 mg per day, or rosuvastatin 5 mg per day.

^§Simvastatin 80 mg per day, atorvastatin 20 mg per day, or rosuvastatin 10 mg per day.

^‖Premature defined as younger than 55 years in men and younger than 60 years in women.