Table 1.
Characteristics of dengue infected and HIV plus dengue co-infected patients.
| Dengue (55) | HIV + Dengue (29) | p value | |
|---|---|---|---|
| Age, years | 35 (28–45) | 41 (33–46) | 0.3697 |
| Gender, male | 31 (56%) | 20 (68%) | 0.3483 |
| Platelet count, ×103/mm3 | 109 (80.5–153.8) | 137.5 (84–169.5) | 0.4053 |
| Hematocrit, % | 40.2 (37.5–42.3) | 38.8 (34.9–40.1) | 0.0241 |
| Albumin, g/dL | 3.6 (3.4–3.9) | 3.6 (3.3–4.0) | 0.7806 |
| TGO/AST, IU/L | 53.5 (31.3–106.8) | 51 (33.5–100.8) | 0.9678 |
| TGP/ALT, IU/L | 74.5 (49–123.8) | 57.5 (46–83) | 0.0463 |
| Mild dengue | 26 (47.2%) | 17 (58.6%) | 0.3647 |
| Dengue with warning signsa | 26 (47.2%) | 11 (37.9%) | 0.4911 |
| Severe dengueb | 3 (5.5%) | 1 (3.5%) | 1.0000 |
| Hemorrhagic manifestations | 24 (43.6%) | 8 (27.6%) | 0.1656 |
| Major bleedc | 11 (20%) | 1 (3.45%) | 0.0501 |
| Petechiae and exanthema | 18 (32.7%) | 5 (17.24%) | 0.1979 |
| Intravenous fluid resuscitation | 18 (32.7%) | 14 (48.3%) | 0.2371 |
| Secondary infectiond | 41 (74.5%) | 21 (72.4%) | 1.0000 |
| PCR positive | 27 (49.1%) | 15 (51.7%) | 0.6494 |
| DENV-1 | 15 (55.5%) | 10 (66.6%) | 0.5115 |
| DENV-2 | 0 (0%) | 1 (6.6%) | 0.3750 |
| DENV-4 | 12 (44.5%) | 4 (26.6%) | 0.3175 |
| IgM positive | 48 (87.3%) | 24 (82.8%) | 0.7440 |
| IgG positive | 45 (81.8%) | 26 (89.7%) | 0.5276 |
| NS1 positivee | 18 (32.7%) | 9 (31%) | 1.0000 |
Data are expressed as median (interquartile range) or number (%). aAbdominal pain or tenderness, persistent vomiting, clinical fluid accumulation, mucosal bleed or increased hematocrit concurrent with rapid decrease in platelet count, according to WHO criteria (2009). bSevere plasma leakage, fluid accumulation and severe bleeding, according to WHO criteria (2009). cGastrointestinal bleed, vaginal bleed and/or hematuria. dPatients that have been previously infected by a different DENV serotype. eDENV nonstructural protein 1 (NS1) antigenemia. ALT, alanine aminotransferase; AST, aspartate aminotransferase; TGO, glutamicoxalacetic transaminase; TGP, glutamic-pyruvic transaminase.