TABLE 3.
Differentially expressed genes related to malonate utilizationa
| Locus | Gene | Product | Fold changea
|
||
|---|---|---|---|---|---|
| TP | SBP | TIM | |||
| PA14_02550 | mdcA | Malonate decarboxylase subunit alpha | 5.9b | 12.1b | 3.1c |
| PA14_02560 | PA14_02560 | Triphosphoribosyl-dephospho-CoA synthase | 4.2 | 20.7 | 3.1 |
| PA14_02570 | mdcC | Malonate decarboxylase subunit delta | 6.0 | 11.6 | 3.3 |
| PA14_02580 | mdcD | Malonate decarboxylase subunit beta | 3.0 | 13.2 | 3.23 |
a
PA14 was grown in blood from TPs, SBPs, or thermally injured mice (TIM) and compared with PA14 grown in blood from HVs or healthy mice.
b
Values obtained by RNA-seq, q < 0.01.
c
Values obtained by RT-qPCR, P < 0.01 (n = 3).