Figure 1.

Docking and crystallographic results for β₂AR. (A) and (B) show surfaces on the IC side for structures 3D4S and 5D5A, respectively. Cholesterol molecules are shown in ball and stick mode: crystallographic structures, green and docked structures, yellow. Oxygen atoms are colored red. Sites are labeled as in Table 1. For the 3D4S structure, 1-oleoyl-R-glycerol (magenta) is observed at site C in the crystal structure. The IC side of the hydrophobic slab representing the bilayer core is shown by the blue bar. To see this figure in color, go online.