Figure 2.

AIP Regulates GC Formation

(A–C) GC B cells (B220⁺ GL7⁺ CD95⁺; in A) and percentage of GC B cells from Aip^fl/fl Cre⁺ mice (B; see also Figures S1C–S1F) and ratio of GCs between Aip^fl/fl Cre⁺ and Cre⁻ mice (C).

(D and E) Lower expression of BCL6 as determined by flow cytometry (D) measuring the median fluorescent intensity (MFI; in E) (see also Figures S2–S4). Grey histograms represent biological control by gating on naive (IgD^hi) B cells that do not express BCL6.

Results are from two or three independent experiments with two to four animals per experiment. ^∗p < 0.05; ^∗∗p < 0.01; ^∗∗∗p < 0.001.