Table 3.

Analysis of the Interaction Interface of Fab_HL and Fc

FabHL	Fc Portion	Distance/Å	Interaction
L:Ser 203 [OG]	K:Ser 331 [OG]	3.8	Hydrogen bond
L:Thr 20 [OG1]	K:Ser 400 [OG]	2.7	Hydrogen bond
L:Thr 20 [N]	K:Ser 400 [O ]	2.9	Hydrogen bond
L:Ser 202 [O]	K:Glu 333 [N ]	2.7	Hydrogen bond
L:Glu 143 [OE2]	K:Lys 340 [NZ]	3.7	Hydrogen bond
L:Glu 143 [OE2]	K:Lys 340 [NZ]	3.7	Salt bridge
L:Arg 18 [NE]	H:Asn 390 [OD1]	3.3	Hydrogen bond
L:Lys 169	H:Phe 296	4.5	π-π interaction
L:Asp 170	H:Phe 296	4.5	π-π interaction

Data generated using PISA software (53).