Table 5.
Comparison of tumor responses according to the RECIST and PERCIST
| Tumor response by RECIST | Tumor response by PERCIST |
Total | |||
|---|---|---|---|---|---|
| CMR | PMR | SMD | PMD | ||
| CR | 8 | 0 | 0 | 0 | 8 |
| PR | 31 | 78 | 6 | 0 | 115 |
| SD | 11 | 85 | 60 | 24 | 180 |
| PD | 4 | 7 | 13 | 80 | 104 |
| Total | 54 | 170 | 79 | 104 | 407 |
The level of concordance of tumor responses between the RECIST and PERCIST 1.0 is 0.389 (unweighted κ, with 95% confidence interval, 0.323 to 0.456). The overall response rates were significantly different between two criteria (30.2% by RECIST vs. 55.0% by PERCIST, p < 0.0001).
RECIST, Response Evaluation Criteria in Solid Tumors; PERCIST, Positron Emission Tomography Response Criteria in Solid Tumors; CMR, complete metabolic response; PMR, partial metabolic response; SMD, stable metabolic disease; PMD, progressive metabolic disease; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease.