Table 4. Six-Month Change in Anhedonia Symptoms and Association Between Left Ventral Striatum Activation to Reward Prediction Error and Improved Life Satisfaction.
| LIFE-RIFT Domain | Mediation Model, β (P Value) | Mediation Effect Size | SE (Bootstrapping Bias-Corrected 95% CI) | |
|---|---|---|---|---|
| Direct (c′ Path) Association | Total (c Path) Association | |||
| Total | −0.013 (.66) | 0.017 (.60) | 1.779 | 0.019 (0.003 to 0.081) |
| Work | −0.018 (.81) | 0.020 (.81) | 1.900 | 0.040 (−0.029 to 0.136) |
| Interpersonal relationships | −0.032 (.73) | 0.080 (.41) | 1.401 | 0.060 (0.023 to 0.264) |
| Satisfactiona | 0.133 (.16) | 0.245 (.01) | 0.456 | 0.060 (0.026 to 0.262) |
| Recreation | −0.095 (.14) | −0.113 (.12) | 0.156 | 0.034 (−0.103 to 0.041) |
Abbreviation: LIFE-RIFT, Range of Impaired Functioning Tool.
a
Significant at P < .05 with Bonferroni correction.