Table 1. Baseline Characteristics of Patients With Ischemic and Nonischemic Cardiomyopathy.
| Characteristic | No. (%) | |
|---|---|---|
| Ischemic Cardiomyopathy (n = 4717) | Nonischemic Cardiomyopathy (n = 7021) | |
| Sex | ||
| Male | 2814 (59.7) | 3892 (55.4) |
| Female | 1903 (40.3) | 3128 (44.6) |
| Age at diagnosis, y | ||
| Mean (SD) | 70.2 (10.6) | 70.0 (12.3) |
| Median (IQR) | 71.0 (63.0-78.0) | 71.0 (62.0-79.0) |
| Race/ethnicity | ||
| White | 3465 (74.5) | 3848 (55.8) |
| Hispanic/Latino | 150 (3.2) | 557 (8.1) |
| Afro-Caribbean | 11 (0.2) | 46 (0.7) |
| Asian (not Chinese) | 596 (12.8) | 2035 (29.5) |
| Chinese | 337 (7.2) | 267 (3.9) |
| Mixed/other | 92 (2.0) | 144 (2.1) |
| Height, cm | ||
| Mean (SD) | 167.7 (9.6) | 165.5 (11.0) |
| Median (IQR) | 168.0 (160.0-175.0) | 165.0 (158.0-173.0) |
| Weight, kg | ||
| Mean (SD) | 80.7 (18.7) | 77.2 (21.4) |
| Median (IQR) | 80.0 (68.0-92.0) | 75.0 (62.0-90.0) |
| BMI | ||
| Mean (SD) | 28.6 (5.8) | 28.0 (6.4) |
| Median (IQR) | 28.0 (25.0-32.0) | 27.0 (24.0-31.0) |
| Pulse, bpm | ||
| Mean (SD) | 88.6 (25.1) | 95.2 (27.6) |
| Median (IQR) | 82.0 (70.0-100.0) | 90.0 (75.0-112.0) |
| Systolic BP, mm Hg | ||
| Mean (SD) | 132.0 (19.7) | 132.0 (20.9) |
| Median (IQR) | 130.0 (120.0-142.0) | 130.0 (120.0-144.0) |
| Diastolic BP, mm Hg | ||
| Mean (SD) | 79.8 (12.7) | 80.2 (14.1) |
| Median (IQR) | 80.0 (70.0-90.0) | 80.0 (70.0-90.0) |
| LVEF, % | ||
| Mean (SD) | 46.9 (14.1) | 45.9 (15.3) |
| Median (IQR) | 48.0 (35.0-58.0) | 45.0 (34.0-59.0) |
| LVEF category | ||
| <40% | 1170 (32.4) | 1892 (37.8) |
| ≥40% | 2436 (67.6) | 3113 (62.2) |
| Care setting specialty at diagnosis | ||
| Internal medicine | 794 (16.8) | 1363(19.4) |
| Cardiology | 3514 (74.5) | 4812 (68.5) |
| Neurology | 27 (0.6) | 60 (0.9) |
| Geriatrics | 9 (0.2) | 43 (0.6) |
| Primary care/general practice | 373 (7.9) | 743 (10.6) |
| Type of AF diagnosed | ||
| Permanent | 710 (15.1) | 1126 (16.0) |
| Persistent | 724 (15.3) | 1493 (21.3) |
| Paroxysmal | 1025 (21.7) | 1395 (19.9) |
| New onset (unclassified) | 2258 (47.9) | 3007 (42.8) |
| Congestive heart failure NYHA class | ||
| I | 544 (13.7) | 1281 (23.2) |
| II | 1952 (49.2) | 2663 (48.1) |
| III | 1285 (32.4) | 1348 (24.4) |
| IV | 183 (4.6) | 241 (4.4) |
| Unknown, No. | 294 | 606 |
| Coronary artery disease | 4365 (92.5) | NA |
| Acute coronary syndrome | 1695 (36.7) | NA |
| Vascular disease | 2200 (47.3) | 327 (4.7) |
| Coronary artery bypass graft | 490 (10.8) | NA |
| PCI with stenting | 1041 (22.1) | NA |
| Carotid occlusive disease | 199 (4.2) | 169 (2.4) |
| Stroke/TIA | 596 (12.6) | 684 (9.7) |
| Systemic embolization | 26 (0.6) | 45 (0.6) |
| History of bleeding | 160 (3.4) | 193 (2.8) |
| History of hypertension | 3985 (84.6) | 5121 (73.1) |
| Hypercholesterolaemia | 2530 (55.7) | 2303 (34.0) |
| Diabetes | ||
| Type 1 | 52 (1.1) | 62 (0.9) |
| Type 2 | 1335 (28.3) | 1415 (20.2) |
| Alcohol consumption | ||
| Abstinent | 2284 (55.3) | 3411 (55.8) |
| Light | 1456 (35.3) | 1822 (29.8) |
| Moderate | 317 (7.7) | 667 (10.9) |
| Heavy | 70 (1.7) | 216 (3.5) |
| Unknown, No. | 590 | 905 |
| Smoker | ||
| No | 2727 (62.0) | 4229 (65.4) |
| Former smoker | 1155 (26.3) | 1473 (22.8) |
| Current smoker | 518 (11.8) | 769 (11.9) |
| Chronic renal disease | ||
| I | 816 (20.0) | 1545 (24.9) |
| II | 639 (15.6) | 882 (14.2) |
| III | 635 (15.5) | 793 (12.8) |
| IV | 95 (2.3) | 129 (2.1) |
| V | 34 (0.8) | 38 (0.6) |
| None | 1868 (45.7) | 2821 (45.4) |
| Moderate-to-severe CKD | 764 (16.2) | 930 (13.7) |
| CHA2DS2-VASc score | ||
| Mean (SD) | 4.4 (1.6) | 3.8 (1.5) |
| Median (IQR) | 4.0 (3.0-5.0) | 4.0 (3.0-5.0) |
| HAS-BLED score | ||
| Mean (SD) | 1.8 (0.9) | 1.4 (0.9) |
| Median (IQR) | 2.0 (1.0-2.0) | 1.0 (1.0-2.0) |
Abbreviations: AF, atrial fibrillation; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); BP, blood pressure; CKD, chronic kidney disease; IQR, interquartile range; LVEF, left ventricular ejection fraction; NA, not applicable; NYHA, New York Heart Association; PCI, percutaneous coronary intervention; TIA, transient ischemic attack.