Table 4.
Estimated cut-points of FIB and results of Cox models with discretized FIB
| Method | cut-point 1 | cut-point 2 | β 1 | HR 1 | P-value1 | β 2 | HR 2 | p-value2 |
|---|---|---|---|---|---|---|---|---|
| Median | 4.52 | – | 0.43 | 1.54 | 0.002 | – | – | – |
| Q1Q3 | 3.59 | 5.84 | −0.33 | 0.72 | 0.059 | 0.17 | 1.18 | 0.295 |
| minP | 4.02 | – | 0.46 | 1.59 | 0.001 | – | – | – |
| OEHR | 2.62 | 4.06 | 1.08 | 2.94 | < 0.001 | 0.61 | 1.83 | < 0.001 |
Median denotes using the median value of the continuous covariate as a cut-point. Q1Q3 denotes using the upper and lower quartiles values as cut-points. MinP denotes the single cut-point minimum p-value method with the log-rank test. OEHR denotes the optimal equal-HR method proposed in this study