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. 2019 May 9;11:73. doi: 10.1186/s13148-019-0674-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Schizophrenia PRS methylation exploration with regard to cerebroplacental ratio measured during the third trimester. a Methylation at cg06793497 (EP300 gene) was significantly associated with CPR in the whole sample (n = 54 twin subjects). b Intrapair methylation difference at cg06793497 was significantly associated with intrapair CPR difference (n = 26 twin pairs)