Table 2.

Effect of survivin expression inhibition on chemosensitivity in hypoxic AMC-HN-8 cells

Drug	IC50 (μg/ml)
	Untreated control	Negative control	Survivin-siRNA
Paclitaxel	37.22×10-3±0.14	37.31×10-3±0.15	10.62×10-3±0.32∗
5-Fu	234.28±0.27	227.12±0.18	92.22±0.41∗
Doxorubicin	3.84±0.83	3.80±0.28	2.67±0.14∗
Gemcitabine	36.77±0.12	37.24±0.19	27.62±0.18∗
Cisplatin	8.22±0.36	8.52±0.42	5.72±0.14∗

IC₅₀ is the concentration of each drug that caused a 50% reduction in the number of cells.

Mean ± SD of three individual experiments are shown. ∗: P < 0.05 vs. Untreated control and Negative control.