Table 2.
MFC values (μmol/mL) and MFC/MIC ratio for compounds 1-12.
| Compounds | Candida albicans | Candida glabrata | Candida krusei | Candida guilliermondi | ||||
|---|---|---|---|---|---|---|---|---|
| (ATCC 90028) | (ATCC 90030) | (ATCC 34135) | (ATCC 22017) | |||||
| MFC | MFC/MIC | MFC | MFC/MIC | MFC | MFC/MIC | MFC | MFC/MIC | |
| 1 | 10.18 | 2 | 5.09 | 1 | + | 1.27 | 1 | |
|
| ||||||||
| 2 | 4.75 | 1 | 4.75 | 1 | 4.75 | 1 | 1.19 | 1 |
|
| ||||||||
| 3 | + | + | + | 2.22 | 1 | |||
|
| ||||||||
| 4 | + | + | + | 2.22 | 1 | |||
|
| ||||||||
| 5 | + | 4.19 | 1 | + | 2.09 | 1 | ||
|
| ||||||||
| 6 | 2.08 | 1 | 2.08 | 1 | 4.16 | 1 | 0.13 | 1 |
|
| ||||||||
| 7 | + | 3.96 | 1 | + | + | |||
|
| ||||||||
| 8 | 3.10 | 1 | 3.10 | 1 | 3.10 | 1 | 1.55 | 2 |
|
| ||||||||
| 9 | + | + | + | 0.40 | 1 | |||
|
| ||||||||
| 10 | + | + | + | 0.41 | 1 | |||
|
| ||||||||
| 11 | 1.58 | 1 | 1.58 | 1 | 0.78 | 1 | 0.024 | 1 |
|
| ||||||||
| 12 | 2.85 | 1 | 2.85 | 1 | 2.85 | 1 | + | |
(+) The compounds present no MFC.
MFC/MIC relation ≥ 4: fungistatic activity. MFC/MIC < 4: fungicidal activity [14].
∗ MFC: minimal fungicidal concentration; MIC: minimum inhibitory concentration.