Table 2.
Distribution of Participants With Unexplained Hypertrophy by Race/Ethnicity
| Total | White | Chinese | African American | Hispanic | P Value | |
|---|---|---|---|---|---|---|
| Unexplained hypertrophy, n (% total cohort) | 67 (1.4) | 25 (1.3) | 6 (0.9) | 23 (1.8) | 13 (1.2) | 0.38 |
| Extenta, n (% participants with unexplained hypertrophy) | 0.02 | |||||
| Focal (2 segments) | 17 (25.4) | 6 (24) | 5 (83.3) | 3 (13.0) | 3 (23.1) | |
| Intermediate (3–7 segments) | 44 (65.7) | 17 (68.0) | 1 (16.7) | 16 (69.6) | 10 (76.9) | |
| Diffuse (≥8 segments) | 5 (7.5) | 1 (4.0) | 0 | 4 (17.4) | 0 | |
| Locationb, n (% participants with unexplained hypertrophy) | ||||||
| Septum | 35 (52.2) | 13 (52.0) | 2 (33.0) | 13 (56.5) | 7 (53.9) | 0.83 |
| Lateral wall | 50 (74.6) | 19 (76.0) | 5 (83.3) | 16 (69.6) | 10 (76.9) | 0.93 |
| Anterior wall | 36 (53.7) | 14 (56.0) | 2 (33.0) | 12 (52.2) | 8 (61.5) | 0.76 |
| Inferior wall | 19 (28.4) | 10 (40.0) | 0 | 7 (30.4) | 2 (15.4) | 0.19 |
| Phenotypeb, n (% participants with unexplained hypertrophy) | ||||||
| Asymmetric septal | 21 (31.3) | 7 (28.0) | 2 (33.0) | 7 (30.4) | 5 (38.5) | 0.96 |
| Isolated basal septal | 4 (6.0) | 1 (4.0) | 1 (16.7) | 2 (8.7) | 0 | 0.36 |
| Apical | 26 (38.9) | 9 (36.0) | 2 (33.0) | 11 (47.8) | 4 (30.8) | 0.77 |
| Midventricular | 44 (65.7) | 17 (68.0) | 3 (50.0) | 15 (65.2) | 9 (69.2) | 0.89 |
| Basal | 47 (70.2) | 18 (72.0) | 3 (50.0) | 18 (78.3) | 8 (61.5) | 0.20 |
a
One participant was not classifiable because of missing data.
b
Participants can be counted multiple times because the definition of unexplained hypertrophy requires 2 adjacent hypertrophied segments in 1 or across levels.