Table 1.
Patient Demographics of the Cohort of Patients Identified From the 51 Heart Team Meetings Conducted Between April 2012 and April 2013
| Demographics | Overall, n=366 | PCI, n=127 | CABG, n=102 | OMT, n=137 | P Value |
|---|---|---|---|---|---|
| Age, y | 69±11 | 68±10 | 66±10 | 72±11 | 0.002 |
| Sex, male | 310 (84.7) | 92 (72.4) | 87 (85.3) | 131 (95.6) | 0.077 |
| BMI, kg/m2 | 28±6 | 28±5 | 28±6 | 28±6 | 0.092 |
| Previous MI | 171 (46.7) | 58 (45.7) | 62 (60.8) | 51 (37.2) | 0.005 |
| Previous PCI | 74 (20.2) | 35 (27.6) | 20 (19.6) | 19 (13.9) | 0.218 |
| Previous CABG | 35 (9.6) | 17 (13.4) | 6 (5.9) | 12 (8.8) | 0.255 |
| Diabetes mellitus | 110 (30.1) | 43 (33.9) | 27 (26.5) | 40 (29.2) | 0.723 |
| Hypertension | 247 (67.5) | 96 (75.6) | 82 (80.4) | 69 (50.4) | 0.298 |
| Cholesterola | 192 (52.5) | 108 (85.0) | ··· | 82 (59.9) | 0.742 |
| Smoking history | 186 (50.8) | 67 (52.8) | 72 (70.6) | 47 (34.3) | 0.191 |
| Chronic kidney disease | 30 (8.2) | 7 (5.5) | 3 (2.9) | 20 (14.6) | 0.644 |
| PVD | 16 (4.4) | 4 (3.1) | 7 (6.9) | 5 (3.6) | 0.500 |
| LV dysfunction (EF<50%) | 125 (34.2) | 22 (17.3) | 40 (39.2) | 63 (46.0) | 0.017 |
| LMS disease (>50%) | 86 (23.5) | 29 (22.8) | 30 (29.4) | 27 (19.7) | 0.693 |
| Coronary disease >50%b | |||||
| 1 vessel | 35 (9.6) | 12 (9.4) | 4 (3.9) | 19 (13.9) | 0.064 |
| 2 vessels | 91 (24.9) | 42 (33.1) | 21 (20.6) | 28 (20.4) | 0.220 |
| 3 vessels | 180 (49.2) | 53 (41.7) | 73 (71.6) | 54 (39.4) | 0.027 |
| SYNTAX score | 30 (23–39) | 29 (21–37) | 31 (25–39) | 31 (23–40) | 0.149 |
| Logistic EuroScore | 4.9 (2.7–9.9) | 6.2 (2.9–12.5) | 3.9 (1.9–6.5) | 6.4 (12.9–12.7) | 0.003 |
| Clinical presentation | |||||
| ACS/unstable angina | 145 (39.6) | 53 (41.7) | 43 (42.2) | 49 (35.8) | 0.296 |
| Cardiogenic shock | 13 (3.6) | 6 (4.7) | 1 (1.0) | 6 (4.4) | 0.336 |
| CCS class | |||||
| 1 to 2 | 145 (39.6) | 42 (33.1) | 42 (41.2) | 61 (44.5) | 0.274 |
| 3 to 4 | 144 (39.3) | 50 (39.4) | 47 (46.1) | 47 (34.3) | 0.049 |
| NHYA | |||||
| 1 to 2 | 197 (53.8) | 75 (59.1) | 77 (75.5) | 45 (32.8) | 0.003 |
| 3 to 4 | 115 (31.4) | 33 (26.0) | 22 (21.6) | 60 (43.8) | 0.003 |
Demographics are reported in the overall population and according to treatment arm. Unadjusted P values are displayed and used to compare characteristics between the treatment arms. Categorical data are described as n (%), where n is the total number of patients identified as fulfilling the specified demographic and (%) is the percentage. Continuous data are described as mean±SD; data that are not normally distributed are described as median (interquartile range). ACS indicates acute coronary syndrome; BMI, body mass index; CABG, coronary artery bypass grafting; CCS, Canadian Cardiac Society; EF, ejection fraction; LMS, left main stem; LV, left ventricle; MI, myocardial infarction; NYHA, New York Heart Association; OMT, optimal medical therapy; PCI, percutaneous coronary intervention; PVD, peripheral vascular disease; SYNTAX, Synergy between PCI with Taxus and Cardiac Surgery.
Data on hypercholesterolemia were not available in the surgical cohort.
Coronary disease not including left main stem disease.