Table 3.
Summary of Vasoactive Agents Within the Pulmonary Circuit
| Agent | Mechanism | Route | Side Effects |
|---|---|---|---|
| Nitric Oxide | ↑ cGMP | Inhaled | Blurred vision, confusion, sweating, malaise, headache, bleeding |
| Milrinone | Phosphodiesterase 3 inhibitor | Intravenous | Bleeding, hypotension, chest pain, tremors, bronchospasm, hypokalemia |
| Prostacyclin | ↑ cAMP, ↑ K, ↓ ET‐1, and ↑ K+ | Inhaled or Intravenous | Bleeding, arrhythmias, diarrhea, edema, fevers, chills |
| Dobutamine | B agonist | Intravenous | Hypotension, tachyarrhythmia, headache, thrombocytopenia |